Epimedium Extract

Epimedium Extract

Epimedium is a commonly used Chinese medicine with high medicinal value. It is a perennial herb with a plant height of 20-60 cm. The rhizome is thick and short, woody, dark brown, and the stem is upright, ridged, hairless, and usually without basal leaves. It is distributed in Jilin, Liaoning, Shandong, Jiangsu, Jiangxi, Hunan and other places. It grows on hillsides and in grass under forests and likes shady and wet areas. It nourishes yin and yang, strengthens yang and strengthens the body.

Basic information
Chinese alias: Icariin; Icariin; Icari extract; Icariin

Icari extract

Latin name
Active ingredients: stems and leaves contain icariin and epinedoside A; rhizomes and roots contain noricarliin and I-cariresinol.

Specifications: Icariin monoglycoside HPLC: 10%-90%.

Properties: Brown-yellow powder

Function: Epimedium is a traditional Chinese medicine tonic that can nourish the kidneys, strengthen the pelvis, and eliminate rheumatism. It is used for impotence, spermatorrhea, pelvic weakness, rheumatic pain, numbness, cramps, and menopausal hypertension. It can effectively inhibit Staphylococcus and resist aging. Icariin is one of its active ingredients, which can effectively improve the cardiovascular system, adjust endocrine, and improve endocrine. In addition, it is particularly noteworthy that epimedium also has anti-cancer effects and is regarded as the most promising anti-cancer drug.

Physical and chemical properties: Molecular formula: C33H40O15

CAS NO.: 489-32-7

Source: This product is the dried aerial parts of the Berberidaceae plants Epimedium brevicornum maxim., Epimedium sagittatum (sieb.et zucc.) maxim., Epimedium pubescens maxim., Epimedium wushanense t.s.ying, or Epimedium nakai. Harvested in summer and autumn when the stems and leaves are lush, the thick stems and impurities are removed, and the ethanol extract is dried in the sun or shade.

Efficacy research
Epimedium extract can increase cardiovascular blood flow, promote hematopoiesis, immune function and bone metabolism, and has the effects of tonifying kidney and strengthening yang, anti-aging, and anti-tumor. Pharmacological studies have shown that it has been confirmed that epimedium can improve sexual ability through various mechanisms such as increasing semen secretion and testosterone production, enhancing energy and sex hormone production. It is also used to treat kidney discomfort in traditional Chinese medicine. Modern research confirms that epimedium can enhance immune function by inducing the production of a series of immune substances. In addition, there are also reports that epimedium has the function of stimulating red blood cell production and improving cerebral blood flow, which establishes the basis for its use in the treatment of cardiovascular diseases.

Reproductive system
Aphrodisiac research

The aphrodisiac effect of epimedium has been confirmed in animal and human studies. Mice treated with epimedium products have a significant effect on enhancing sexual desire. Its efficacy is also manifested by increasing semen secretion.

Because Epimedium is traditionally used to treat kidney disease, studies have shown that it has a sexual enhancement effect and can improve the quality of life of patients with chronic renal insufficiency who take Epimedium. In addition, studies have shown that Epimedium has anti-fatigue effects and helps prevent adrenal failure.

Epimedium is a commonly used Chinese medicine for kidney tonification. Epimedium has a promoting effect on the function of the pituitary-gonadal system, can improve male gonadal damage, increase testosterone content, and promote the secretion of corticosterone by adrenal cortical cells. The kidney-tonifying and yang-enhancing effect of Epimedium is related to its direct stimulation of target glands to secrete hormones. Epimedium can promote sexual function due to hypersecretion of semen, which stimulates sensory nerves after the seminal vesicles are filled, and indirectly stimulates sexual desire.

Mechanism of Action

Studies have shown that Epimedium significantly increases testosterone in mice. For example, it has been confirmed that sexual impulse is associated with cholinergic neurotransmitters, but there is a class of enzymes called acetylcholinesterase (AchE) that can inactivate cholinergic neurotransmitters. As an inhibitor, research has found that epimedium can inhibit AchE. Such inhibitory effects may maintain high levels of key cholinergic neurotransmitters associated with sexual drive.

Clinical Research

Cardiologist Hugo Mana Sanpina, MD, first discovered the efficacy of epimedium in a decade of research on a group of older men who were still sexually active and had good results taking the herbal remedy. And Gary F. Gordon, a Chicago physician and former president of the American Academy of Medical Development, also believes that epimedium is a way to normalize steroid hormones such as testosterone, progesterone and estrogen in the body. So it can effectively prevent hormonal changes caused by aging. It plays a role in restoring normal healthy functional status in men so that they can experience more active sexual drive. "

Immune system
Epimedium polysaccharide has the effect of enhancing the body's immune function, and can enhance and maintain normal adrenal cortex function and immune function.

Anti-aging
Epimedium affects the aging mechanism from different aspects, which can delay the aging process and prevent the occurrence of geriatric diseases. For example, it affects cell generation, prolongs the growth period, regulates the immune and secretory systems, and improves the body's metabolism and organ functions.

Cardiovascular
Using epimedium extract, it can reduce cerebrovascular resistance, and has a certain protective effect on myocardial ischemia caused by posterior pituitary hormone, and has a scientific basis for the treatment of coronary heart disease and angina pectoris.

Effect on blood
Epimedium polysaccharide inhibits platelet aggregation reaction, inhibits thrombosis; and can promote the differentiation and proliferation of various blood cells and promote hematopoietic function.

Promote metabolism
Epimedium has the effect of promoting DNA synthesis

Anti-osteoporosis
Experiments have shown that epimedium has the effect of promoting the synthesis of DNA in bone cancer cells, has a "bone-replenishing" effect, and has a good preventive and therapeutic effect on osteoporosis.

The full English name of epimedium extract is Epimedium Extract, the extract is from the Berberidaceae plant Epimedium, which has the effects of tonifying the kidney and strengthening yang, relieving cough and asthma, dispelling wind and dampness, and invigorating qi and strengthening the heart.