Dandelion root extract

[English name] Dandelion Extract
[Latin name] Taraxacum officinale Wigg.
[Parts used]: Whole herb
[Source] Dried whole herb of Taraxacum mongolicum Hand.-Mazz., Taraxacum sinicum Kitag. or several plants of the same genus
[Chemical ingredients] Contains taraxasterol, choline, inulin, pectin, taraxasterol, taraxein, taraxetriol, caffeic acid and other ingredients.
[Appearance] Brown-yellow fine powder
[Specification] Dandelion flavonoids 5% 8%
Ratio 10:1
[Testing method] SC enterprise standard filing

II. Specifications of dandelion extract

Product name Specification Testing method Appearance
Dandelion extract Dandelion flavonoids 5% UV Brown-yellow fine powder
Dandelion flavonoids 8% UV
Ratio 10:1 TLC

III. Efficacy and application of dandelion extract
According to the 2015 edition of the Chinese Pharmacopoeia:
Dandelion nature and flavor: bitter, sweet, cold.
Meridians: Liver and stomach meridians.
Efficacy: Clearing away heat and detoxifying, reducing swelling and dispersing knots, diuresis and relieving stranguria.
Indications: Used for carbuncle swelling, breast carbuncle, scrofula, red eyes, sore throat, lung carbuncle, intestinal pain, damp-heat jaundice, hot stranguria and astringent pain.
Usage and dosage: 9-15g.

4. Pharmacological effects of dandelion extract

Dandelion is a food and medicine. Our company has SC production license for dandelion powder. Dandelion extract has been approved by the US FDA as a GRAS (generally recognized as safe) food ingredient. The extract is used as a flavor ingredient in a variety of edible products, including beverages, frozen desserts, candies, baked goods, jellies, puddings and cheese. Dandelion extract has a wide range of antibacterial effects, can promote human immune function, has certain anti-cancer effects, and has certain effects on liver disease. It is used to treat liver and gallbladder obstruction, improve liver function, promote bile secretion and is used as a diuretic.

1. Antibacterial effect
Dandelion injection has a strong bactericidal effect on drug-resistant strains of Staphylococcus aureus and hemolytic streptococci in vitro, and also has a certain bactericidal effect on pneumococci, meningococci, diphtheria bacillus, Pseudomonas aeruginosa, Proteus, Shigella dysenteriae, Salmonella typhi and catarrhalis. Dandelion extract (1:400) can inhibit tuberculosis in vitro. Dandelion decoction (1:80) can delay ECHO11 virus cytopathic effect. Dandelion alcohol extract 31mg/kg can kill Leptospira. The water extract has an inhibitory effect on a variety of skin fungi. The decoction was orally administered to rats and was well absorbed, and a certain antibacterial effect was maintained in the urine.
2. Liver protection and choleretic effect
Animal experiments have shown that oral administration of dandelion decoction or injection of dandelion injection has a significant inhibitory effect on the increase of alanine aminotransferase caused by carbon tetrachloride; it can significantly alleviate the histological changes caused by carbon tetrachloride liver damage. It has been reported that dandelion has a choleretic effect on animals. Intragastric administration of dandelion liquid can cause the gallbladder to contract and the sphincter of Oddi to relax, which is conducive to the discharge of bile into the intestine. It is clinically effective for chronic gallbladder spasm and calculi.

3. Anti-gastric ulcer effect
Dandelion decoction has a significant protective effect on stress ulcers when given to rats by gavage; it also has a significant protective effect on rat gastric mucosal damage caused by anhydrous ethanol; and can significantly resist the formation of gastric ulcers in rats with pyloric ligation. When dandelion is combined with Codonopsis pilosula and Chuanxiong, it has a synergistic anti-gastric ulcer effect, and the anti-ulcer effect of the three-compound is stronger. It has been reported that the mechanism of this compound's anti-gastric ulcer and gastric mucosal damage effect may be related to the influence on the endogenous PGE2 content of gastric tissue. Medical/Education Network Collection and Arrangement.

4. Effect on immune function
Dandelion decoction can significantly increase the blast cell transformation rate of human peripheral blood lymphocytes in vitro. Dandelion polysaccharide can significantly enhance the intensity of delayed-type hypersensitivity reaction of mouse foot pads caused by Ehrlich carcinoma and MM46 tumor cell antigens, and has the characteristic that the later the administration time, the more effective it is, that is, administration on the 11th to 20th day after antigen stimulation or 2 to 20 days after administration has a significant effect. Intraperitoneal injection of dandelion polysaccharide can significantly enhance the cytotoxic effect of antibody-dependent macrophages in mice. Medical/Education Network Collection and Compilation.

5. Other effects

According to surveys, dandelion extract has a good effect in treating edema and diuresis, and also has a good therapeutic effect on other diseases. Many people choose to eat dandelion roots and grass leaves for health care and antidiarrhea. Taking dandelion for snake bites will also have a certain healing ability.